science
Verified · Tested · Proven // ISO 17025 · GLP · cGMP

Science
that speaks
for supplements.

Purpose-built analytical testing lab and CRO for the dietary supplement industry. Verified, validated, and proven — from raw material to retail shelf.

Standard 5–7 days Receipt to COA
Rush 48–72h Select assays
Model 3-in-1 Lab · CRO · Reg
Format Retail Amazon · WFM
CURÍ · VERIFIED · TESTED · CURÍ · VERIFIED · TESTED · est. 2024
C₁₂H₁₇NO₃ / Active
Reference Bond
Science First Integrity Precision Partnership Transparency Science First Integrity Precision Partnership Transparency
mission
001 · Our Mission

The principles that guide every project.

Curí exists to give supplement brands the analytical rigor they need to launch with confidence — bridging laboratory precision and real-world compliance through testing, research, and partnership.

002 · Start Here PATHWAYS

What do you need?

Five common paths brands take with Curí. Select one to see the recommended workflow.

Step 01

Raw Material Testing

Qualify incoming ingredients for identity, purity, heavy metals & microbiological compliance before you manufacture.

Step 02

Formulation Review

Ingredient compatibility, dose guidance relative to literature, and excipient selection review.

Step 03

Finished Product Testing

Full release testing against USP, AOAC, or in-house validated methods. Potency, micro, heavy metals, physical.

Step 04

Retail-Ready COA Issuance

Formatted to meet documentation standards required by Amazon, Whole Foods, iHerb, and major brick-and-mortar platforms.

Amazon

Supplement Testing & Transparency

Curí COAs are formatted to Amazon's supplement compliance documentation requirements out of the box.

WFM · iHerb

Vendor Qualification Packages

Full vendor onboarding documentation including COA formatting, SOP development, and third-party audit preparation.

All Retailers

COA + SOP Development

Tailored SOPs for incoming material testing, product release, and in-process controls — enabling brands to demonstrate cGMP compliance.

Compliance

21 CFR Part 111 Documentation

Full support for DSHEA label claim documentation and 21 CFR Part 111 cGMP compliance submissions.

Label Claims

Potency / Label Claim Verification

HPLC/MS analytical confirmation that active ingredients are present at declared levels.

DSHEA

Structure / Function Substantiation

Scientific literature review, analytical substantiation packages, and documentation dossiers.

Novel Ingredients

Custom Method Development

For proprietary ingredients where compendial methods don't exist, Curí develops and validates custom analytical methods.

Shelf Life

Stability & Expiry Claims

Accelerated and real-time stability programs per ICH guidelines. Data to support end-of-shelf-life label claims.

Identity

FTIR / NIR / HPLC Identity Testing

Comparison against reference standards to confirm you received what you ordered.

Purity

Adulteration Screening

HPLC-UV/PDA and FTIR pattern matching to detect substituted or diluted materials.

Safety

Heavy Metals & Contaminants

ICP-MS for Pb, As, Cd, Hg and full elemental panel per USP <232> or California Prop 65 limits.

Microbiology

Total Counts + Pathogen Detection

TAMC, TYMC, coliforms, E. coli, Salmonella — and probiotic CFU enumeration with species-selective methods.

NSF · USP

Certification Support Testing

Curí provides the analytical data and documentation stack that certification bodies require.

Documentation

Root Cause Analysis

If a prior application was denied, Curí can perform sample investigation, identity testing, and documentation review.

Audits

Third-Party Audit Preparation

Curí actively supports clients through audit preparation, vendor qualification documentation, and compliance submission packages.

Ongoing

Lot Release Programs

Ongoing testing programs for each production lot — providing consistent COA documentation for continued retail compliance.

003 · Services OUR WORK

All services.

Hover any card to reveal the work. Click to expand the full scope and methods.

Raw Material

Raw Material Testing

Incoming qualification per 21 CFR Part 111 — identity, purity, strength & composition. Botanical authentication & adulteration screening.

FTIRIdentity
ICP-MSHeavy metals
USP <2021>Micro
21 CFR 111Compliant
Finished Product
COA · CERTIFIED

Finished Product Testing

Full release testing & label claim verification across capsules, powders, gummies, liquids, softgels & tablets.

HPLC/MSPotency
USP <711>Dissolution
6Formats
RetailReady
CRO Services
DEV VAL SOP research ICH Q2(R1)

Contract Research (CRO)

Method development, validation, label claim substantiation & stability studies — GLP-aligned & FTC/FDA defensible.

ICH Q2Validation
DSHEAClaims
GLPAligned
5Modules
Tests Performed
  • Identity: FTIR, NIR, HPLC vs reference standards
  • Purity / adulteration: HPLC-UV/PDA, FTIR pattern matching
  • Heavy metals (Pb, As, Cd, Hg) via ICP-MS
  • Microbiological limits: TAMC, TYMC, coliforms, pathogens
  • Probiotic CFU enumeration
  • Moisture: Karl Fischer or gravimetric LOD
  • Botanical authentication via FTIR/NIR fingerprinting
Regulatory Alignment
  • 21 CFR Part 111 compliant
  • USP <232>/<233> elemental impurities
  • California Prop 65 limits available
  • USP <2021> microbiological limits
  • AOAC or validated in-house methods
Parameters Tested
  • Potency / label claim via HPLC/MS
  • Microbiological compliance (USP <2023>)
  • Heavy metals per USP <232>/<233> or CA Prop 65
  • Moisture content & water activity
  • Dissolution (USP <711>) & disintegration (USP <701>)
  • Hardness & friability for tablets
  • pH & appearance for liquids
Product Formats Supported
  • Capsules (hard-shell gelatin and HPMC)
  • Powders (bulk and sachet)
  • Gummies
  • Liquids (tinctures, emulsions, beverages)
  • Softgels
  • Tablets (coated and uncoated)
CRO Capabilities
  • Custom method development for novel/proprietary ingredients
  • Full ICH Q2(R1) method validation
  • Custom protocols around specific claims or ingredients
  • Label claim substantiation (DSHEA structure/function)
  • Accelerated & real-time stability per ICH
Deliverables
  • Full study reports + data appendices
  • Substantiation dossiers for retail submission
  • Validated SOPs transferred to client QA
  • Stability protocols with time-point data
  • FTC/FDA-defensible documentation packages
capabilities
004 · Capabilities
CAPABILITIES

Tailored science for
modern supplement brands.

We bridge the gap between abstract laboratory chemistry and practical retail-shelf compliance through bespoke analytical engineering.

Start Project
// 001 Autonomous Analytical Lab

Autonomous Analytical Laboratory

// 001

Architecting validated analytical environments and instrument calibration programs to ensure every data point is traceable, reproducible, and defensible under audit.

HPLC/MS ICP-MS
// 002 Finished Product Testing

Finished Product & Release Testing

// 002

Full release testing across all supplement formats. Potency via HPLC/MS, microbiological compliance, heavy metals, dissolution & physical characterization — formatted for direct retail submission.

COA · CERTIFIED PASS USP <711>
// 003 CRO & Custom Methods

CRO & Custom Method Development

// 003

Method development, ICH Q2(R1) validation, label claim substantiation, and stability programs. Every CRO engagement scoped individually for novel ingredients and proprietary formulations.

DEV VAL SOP research ICH Q2(R1)
005 · Why Curí THE DIFFERENCE

Not all labs are the same.

Most labs are high-throughput commodity services. Curí is built differently — purpose-engineered for the supplement industry.

curí
Commodity Lab
Supplement-specialized expertise
Botanical, hormonal, probiotic depth
General-purpose
Integrated CRO capabilities
Testing + CRO + Regulatory under one roof
Testing only — you manage the rest
Retail-ready COA formatting
Amazon, WFM, iHerb — no reformatting
Generic COA format
Label claim substantiation
Literature review + analytical dossiers
Not offered
Dedicated scientific contact
Every client assigned to a scientist
Customer service / ticket queue
Retailer onboarding support
Active submission support
Not offered
Probiotic CFU strain-level testing
Species-selective · shelf-life validated
Bulk count only
Rush turnaround
48–72 hrs for select assays
Varies / premium pricing
006 · Instrumentation LABORATORY

Analytical instruments.

All instruments maintained under documented qualification & calibration schedules per ISO 17025.

// 01
HPLC — UV/PDA & MS Detection

Potency & Identity

Potency assay, label claim verification, identity confirmation, purity assessment. Botanical actives, vitamins, hormonal compounds.

// 02
FTIR & FTNIR — Spectroscopy

Rapid Material ID

Raw material identity testing, fingerprint matching, rapid non-destructive ID, polymer/excipient verification.

// 03
ICP-MS — Heavy Metals

Elemental Analysis

Pb, As, Cd, Hg & full elemental panel per USP <232>. California Prop 65 limits available.

// 04
Dissolution — USP <711>

Release Testing

USP Apparatus 1 (basket) & 2 (paddle). Simulated gastric/intestinal fluid. Tablets, capsules, softgels.

// 05
Disintegration — USP <701>

Tablet & Capsule QC

USP-compliant disintegration testing for tablets & capsules per standard acceptance criteria.

// 06
Moisture & Physical — USP <1217>

Physical Characterization

Loss-on-drying (gravimetric). Tablet hardness & friability per USP standards.

MICROBIOLOGYPathogen detection & probiotic CFU.

TAMC

USP <2021>

Total aerobic microbial count.

TYMC

USP <2021>

Yeast & mold enumeration.

E. coli

Bile-tolerant gram-neg

Pathogen detection per USP.

Probiotic CFU

Species-selective

24-month shelf-life programs.

007 · Certifications QUALITY

Built to the highest standard.

Independently verified competence across every discipline we operate in.

ISO 17025Accredited

ISO/IEC 17025:2017

Independently verified laboratory competence — the international gold standard for testing labs.

G
GLPCompliant

Good Laboratory Practices

Study documentation, data integrity, audit trails, personnel qualifications & QA oversight across all CRO activities.

c
cGMPAligned

21 CFR Part 111 Aligned

COAs, SOPs, deviation records & CAPA systems integrate with clients' manufacturing quality programs.

R
RetailReady

E-Commerce & Retail Compliance

COAs formatted for Amazon, Whole Foods, iHerb, and major health retail platforms.

industries
008 · Industries
WHO WE SERVE

From raw ingredients
to retail shelves.

Serving the full supplement value chain — from R&D labs and ingredient suppliers through contract manufacturers to consumer-facing brands.

// 01Dietary Supplement BrandsThird-party testing, COA issuance, lot release
// 02Nutraceutical & Botanical SuppliersRaw material qualification, identity & purity
// 03Contract Manufacturers (CMOs)Independent QC testing for brand clients
// 04Life Science & Biotech CompaniesPhytochemical profiling & R&D support
// 05Clinical Research OrganizationsGLP-aligned testing for clinical protocols

PRIORITYCategories

Women's Health Sports Nutrition Cognitive Probiotic Herbal & Botanical
009 · Workflow OUR PROCESS

5 steps. 6–7 days.

Iterative, transparent, and engineered for retail-ready output. Rush (48–72 hr) available for select assays.

Day 01 · Intake

Inquiry & Scope

  • Submit via portal or email
  • Scope review & method confirmation
  • Quote issued same day
Day 02 · Receipt

Sample Submission

  • Ship to Cedartown, GA
  • Chain-of-custody initiated
  • Logged into QMS
Day 03+ · Analysis

Testing & Analysis

  • USP / AOAC validated methods
  • Micro panels: +5–7 days incubation
Days 4–5 · Review

Data Review & QA

  • Second scientist review
  • Technical Director sign-off
  • OOS triggers investigation
Days 6–7 · Issue

COA Issuance

  • Retail-ready COA via portal
  • CRO: full study report
Rush: 48–72 hours for select assays · Microbiology per USP <2021> adds 5–7 days for incubation · CRO projects scoped individually at kickoff · All records retained per ISO 17025
010 · Case Studies CASE STUDIES

Real problems. Measurable outcomes.

Selected engagements demonstrating Curí's approach to complex supplement challenges.

Case 01 · Probiotic Validation /// CS-001

50B CFU probiotic blocked by retailer pushback on COA documentation.

+24mo shelf-life·Strain-selective·Cleared retail
+
The Problem

A supplement brand formulating a 50 billion CFU probiotic blend faced retailer pushback. Their existing COA did not specify enumeration methods or end-of-shelf-life viability data — only a manufacture-date count.

Curí's Approach

Species-selective plating using validated methods for each strain, confirming potency at time-of-manufacture and initiating an accelerated stability protocol to model CFU survival through a 24-month shelf life.

Outcome

Brand received a comprehensive COA package with time-point data, method documentation, and a written label claim substantiation summary — clearing retailer requirements.

Case 02 · NSF Recovery /// CS-002

NSF certification denied — documentation failures and adulterated source material.

Root cause·Source audit·NSF achieved
+
The Problem

A supplement brand seeking NSF certification required assistance in compliance and documentation submission, sample investigation, and root cause analysis for previously denied applications.

Curí's Approach

Ingredient sourcing review, documentation audit, identity testing comparing submitted material against authenticated reference standards. FTNIR, microbiology, and material fingerprinting used as secondary confirmation tools.

Outcome

Accelerated rate of product certifications, including previously denied applications — enabling the brand to achieve NSF certification and proceed with retail onboarding.

contact
011 · Contact
GET IN TOUCH

Let's work together.

Every project starts with a conversation. Response within 1 business day — same-day for rush requests.

Website / Portalcuriusa.com
Emailcontact@curiusa.com
Phone478-960-8856
Laboratory

Cedartown, GA
Sample intake · Testing · COA

Office

Atlanta, GA
Client services · CRO · Regulatory

Request a Quote